Known to have hepatoprotective effects, the Antrodia Cinnamomea health product has been believed to aid in the symptoms of various liver diseases and cancer.
The Antrodia Cinnamomea or A. Cinnamomea is a kind of mushroom and is one of the parasitic fungus that belongs in the Antrodia genum. It is believed to be found only in Taiwan and has aided the Taiwanese in relieving symptoms of liver disorders. Most people in Taiwan say that A. Cinnamomea is effective when it comes to protecting the liver. During the earlier years where medicine was not readily available, the Taiwanese people use A. Cinnamomea to cure those who exhibit symptoms of liver disorders, abdominal discomfort and diarrhea. The fungus grows heavily in Taiwan alone and over the years, it has been studied and cultivated in order to aid a lot of illnesses, cancer now included.
Excessive alcohol intake injures the liver. First it starts of with the person having a fatty liver, then it will persist especially if the person neglects medical assistance and prevention. Hepatitis or the inflammation of the liver, is also one of the disorders aided by A. Cinnamomea. It is also believed that the fungus can help prevent Hypertension. Over the years and with the advancement of fermentation and cultivation techniques, A. Cinnamomea now helps with liver health, relieving hypertension, abdominal discomfort, and diarrhea. It has also assisted in the treatment of cancer through the patients who are undergoing chemotherapy. A. Cinnamomea is administered because it aids in the gastrointestinal discomfort that they feel during treatments.
So how does a little fungus help a lot of people? Scientist and other health care specialists modernized the techniques that the people of Taiwan used all those years. After the discovery and the proven effectiveness of A. Cinnamomea, the fungi are now being cultivated and fermented. One of the most effective technique is by using submerged fermentation. Such way is important in order to work on every mushrooms’ identity and purity without the risk of contamination. By way of submerged fermentation, an important vegetative compound of the fungus called the mycelia can be obtained. A mushrooms mycelium is the one that finds nutrients for it to grow. It extends out so that it can find water, potassium, nitrogen, and more. Obtaining a medicinal mushroom’s mycelia requires a crucial process. Every process must be done aseptically and carefully to avoid contamination before it is distributed to the people for treatment.
Antrodia Cinnamomea promotes liver health and is a kind of supplement that can boost an individuals immune system because of its triterpenoids and polysaccharides. Going the natural way is much better simply because it rids your body from chemicals and prevents bad side effects that chemicals give off. Various studies have shown that triterpenoids give off a cytotoxic effect to cancer tumor cells. Antrodia Cinnamomea is may be able to help in treating cancer because some studies also say that natural triterpenoids has a big role in chemoprevention. In one product alone, it helps alleviate a lot of symptoms, from liver disorders, chemo side effects, and gastric or abdominal discomfort. Consult your physician and try Antrodia Cinnamomea health product now.
What is Superoxide Dismutase?
SOD is recognised as the first line of defence against reactive oxygen species (ROS), where ROS impair the function cells and tissues and thought to underlie the pathogenesis of various diseases. SOD catalyses the dismutation of superoxide radical (harmful) into oxygen and hydrogen peroxide (not harmful). However, like many other protective compounds which naturally occur in the body, SOD decreases with age, making cells more vulnerable to oxidative stress. Hence, we need regular SOD supplementation to maintain our health.
Oxidative stress and ROS cause cell damage and are the main cause of numerous pathological conditions, such as chronic inflammation, accelerated aging and cardiovascular diseases. SOD plays an important role in inflammatory diseases by neutralizing superoxide radical without affecting the immunological functions of phagocytes. It is found to have positive effect in countering allergies. Studies have also found demonstrated the protective role of SOD against inflammatory reactions caused by ultraviolet radiation.
Overproduction of ROS has found to lead to a loss of blood vessel tone and hypertension, therefore SOD is used to remove superoxide radical and restores blood pressure to near-to-normal values. The increased in production of ROS through glucose autooxidation has been reported to be the cause of diabetes. Thus, SOD consumption helps increase the antioxidant defences in human body.
The potential therapeutic uses of SOD have been discussed for a several years, and a diet rich in antioxidants supplied from fruits and vegetables is recommended to maintain health. For example, soybean, green tea, grapes, tomatoes and so on due to the high amount of antioxidants found in it.
Researches in France found a variety of cantaloupe melon containing high levels of SOD and this is crucial as the melon extract serves as a protective layer in order to keep SOD safe during the digestive process, since SOD is sensitive to heat and acidity. It is showed that when SOD activity is preserved during the digestive process, it is possible to induce antioxidant and anti-inflammatory effects of it by oral supplementation.
Therefore, SOD dietary supplementation have a protective effects against oxidation stress which can cause damage to our cells leading to various disease. It is important to prevent our cells from exposing to excess oxidative stress in order to maintain a healthy state of the body.
What are triterpenoids?
Triterpenoids is the most important chemical composition in Antrodia Cinnamomea. They are characterized by the basic backbone of a 30-carbon isoprenoid molecule and ubiquitous in the plant kingdom, with potential disease prevention and treatment properties. Recent evidences support the beneficial effects of triterpenoids against several type of human diseases, including various cancers.
Several studies have shown that triterpenoids significantly suppress chronic inflammation by modulating pro-inflammatory mediators. They have the ability to inhibit 5-lipoxygenase (5-LOX), inducible forms of nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and nuclear factor-kB (NF-kB) activities. This is important because excessive and prolonged iNOS-mediated nitric oxide (NO) has been linked to both inflammation and tumorigenesis (the formation of tumour) by inhibiting apoptosis (process of cell-death), enhancing cell proliferation, suppressing immune function and increasing the invasiveness of cancer cells.
There is also clear evidence that suggests naturally-occurring triterpenoids suppress cancer cell growth by interfering with cell cycle regulatory proteins and/or their expression levels. Studies have shown that they induce cell cycle arrest in human colon, oesophageal and non-small cell lung cancer cell lines. Antitumor activity is also reported through induction of apoptosis brought by triterpenoids. Apoptosis is a highly regulated physiological process of cell death characterized by cell shrinkage, nuclear condensation and DNA fragmentation. Triterpenoids interfere with the cancer cell growth process, hence able to kill cancer cells.
The crucial part for cancer cells and tumour to grow is to have their own supply of nutrients, ie tumour angiogenesis. It is the formation of new blood vessels from host vasculature and is critical for tumour growth and metastases, mediated by proangiogenic proteins, such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF). It has been established and shown that triterpenoids are inhibitors of angiogenesis (blood vessel formation) and metastasis (the spreading of cancer cells) by inhibiting any further cell proliferation.
What most people are concern is the anti-carcinogenic activities of triterpenoids. Recent studies showed that triterpenoids significantly inhibit precancerous lesions. For example, triterpenoid such as Glycyrrhizic acid (GA) is used as a major therapeutic agent for anti-inflammation and anti-ulcers in nature. All these show potential chemo preventive effects of triterpenoids.
In conclusion, there has been substantial evidence supporting the anti-inflammatory effects of triterpenoids in a number of in vitro model, with a significant downregulation of inflammatory molecules; convincing evidence of anti-carcinogenic effects of triterpenoids for several cancers with inhibition of tumour cell growth. Given the potential usefulness of triterpenoids, more studies will be conducted in the near future to discover more of its benefits and usage.
The immune system is the body’s defence against infectious diseases. It is very important to build a strong immune system in order to activate immune response, so that it can attack foreign substances that invade the body system that causes disease. A strong immune system does a great job of keeping people healthy and preventing infections.
The immune is made up of a network of cells, tissues, and organs that work together to protect the body. One of the most important key player cells involved are white blood cells, also known as leucocytes, which come in two basic types that can combine to seek out and destroy disease-causing substances.
Leucocytes are produced or stored in many locations in the body, namely the lymphoid organs including the thymus, spleen, and bone marrow. There are also clumps of lymphoid tissue throughout the body, primarily as lymph nodes that house the leucocytes.
The two basic types of leucocytes include phagocytes, cells that engulf invading organisms; lymphocytes, cells that allow the body to remember and recognize previous invaders and help the body destroy them. The most common type of phagocytes is neutrophil, which primarily fights bacteria. Doctors usually order a blood test to see if a patient has an increased number of neutrophils if they are worried about a bacterial infection. There are also two kinds of lymphocytes, namely B lymphocytes and T lymphocytes. Lymphocytes start out in the bone marrow and either stay there and mature in B cells, or they leave for the thymus gland, where they mature into T cells. B lymphocytes and T lymphocytes have separate functions: B lymphocytes are like the body’s military intelligence system, seeking out their targets and sending defences to lock onto them. T cells are like the soldiers, destroying the invaders that the intelligence system has identified.
How do immune system work? When antigens (foreign substances that invade the body) are detected, several types of cells work together to recognize them and respond. These cells trigger the B lymphocytes to produce antibodies, which are specialized proteins that lock onto specific antigens. Once produced, these antibodies stay in a person’s body, so that if his or her immune system encounters that antigen again, the antibodies are already there to do their job. This is how immunizations prevent certain diseases. An immunization introduces the body to an antigen in a way that doesn’t make someone sick, but allow the body to produce antibodies that will then protect the person from future attack by the germ or substance that produces that particular disease.
Although antibodies can recognize an antigen and lock onto it, they are not capable of destroying it without help. That’s the job of the T cells, which are park of the system that destroys antigens that have been tagged by antibodies or cells that have been infected or somehow changed. (Some T cells are actually called “killer cells”.) T cells also are involved in helping signal other cells like phagocytes to do their jobs. Antibodies can neutralize toxins too and activate a group of proteins called complement, which assists in killing bacteria, viruses, or infected cells.
All of these specialized cells and parts of the immune system offer the body protection against disease. This protection is called immunity.
Humans have three types of immunity, innate, adaptive, and passive:
Innate immunity, also known as natural immunity is a type of general protection. Everyone is born with innate immunity. It also includes the external barriers of the body, like the skin and mucous membranes (like those that line the nose, throat, and gastrointestinal tract), which are the first line of defense in preventing diseases from entering the body. If this outer defensive wall is broken (as through a cut), the skin attempts to heal the break quickly and special immune cells on the skin attack invading germs.
The second kind of protection is adaptive (or active) immunity, which develops throughout our lives. Adaptive immunity involves the lymphocytes and develops as people are exposes to diseases or immunized against diseases through vaccination.
Passive immunity is “borrowed” from another source and it lasts for a short time. For example, antibodies in a mother’s breast milk give a baby temporary immunity to diseases the mother has been exposed to. This can help protect the baby against infection during the early years of childhood.
With that said, everyone’s immune system however is different. We can see some people never seem to get infections, whereas others seem to be sick all the time. As people grow older, they usually become immune to more germs as the immune system comes into contact with more and more of them. That’s why adults and teens tend to get fewer colds than kids- their bodies have learned to recognize and immediately attack many of the viruses that cause colds. However, this varies from person to person.
Problems of Immune system
Immune system can go haywire sometimes, which could be in the form of immunodeficiency disorders, autoimmune disorders, allergic disorders and cancers of the immune system.
What we’re more interested in looking at is the cancers of immune system. Cancer happens when cells grow out of control. This can include cells of the immune system. When normal cells turn into cancer cells, some of the antigens on their surface may change. If the immune system notices the foreign antigens, it launches the body’s defenders, including killer T cells, NK cells, and macrophages. But the immune system cannot patrol everywhere to provide body wide surveillance, flushing out and eliminating all cells that become cancerous. Tumours develop when the system breaks down or is overwhelmed. For example, Leukaemia involves abnormal overgrowth of leucocytes while Lymphoma involves the lymphoid tissues.